How Could Liposomes Help as Antiviral Agents Against Coronavirus?
We are familiar with the health benefits of liposomal vitamin C. The thing we don’t know yet is liposomes growing importance in this pandemic situation. According to new scientific research and recent studies, liposomes are also very helpful as antiviral agents against coronavirus.
Using Liposomal Vitamin C Information, How Do You Sterilize Liposomes?
Liposomal vitamin C has enormous popularity and very beneficial to us, and if we want to sterilize the liposomes, we need to find suitable methods like filtration under specified conditions. The sterilization of liposomes is a problematic process because liposomes are sensitive to high temperatures and different ways of radiation.
Sterilizing with chemicals is not a comfortable option either, as it may badly the stability of the liposomes. There is only one suitable method for the formation of sterile liposomes, and that is filtration using a 0.22 μm membrane filter.
This unique technique is not suitable if the size of liposomes is more significant than 0.2 μm in diameter and does not eliminate viruses. Another way is filtering the initial solutions using 0.45 μm regenerated cellulose filters and also glass fiber filters before initiating production; after that, the complete formation process should be done under aseptic conditions.
Why Is Liposomal Vitamin C Better?
Many things prove that liposomal vitamin C is better than your regular vitamin dietary capsules. And one thing that is the reason behind its excellent efficiency is its highly active drug delivery system. We know that the absorption of liposomal vitamin C is incredibly higher than that of any standard vitamin C supplement. The numerous advantages of liposomal vitamin C involve;
- Enhanced bioavailability
- Cardiovascular support
- Increased skin health
- Improved collagen production
- Decreased oxidative stress throughout the body
How is Liposomes Formed?
The liposome can naturally form when there is a disturbance in tissues. Due to any damage to tissue, tinny pieces of the cell membrane may detach. The exposed small parts of lipid bilayer fold again on itself, encapsulating a small packet of solution it forms in. It happens due to the hydrophobic and hydrophilic interactions between different pieces of the lipid bilayer and also the surrounding aqueous solution. It compels the ends of the pieces, where there is expose the hydrophobic core, to come together and make a sealed internal pouch.
Utilizing a sonic wave generator, scientists can use sonic waves to separate lipid bilayer membranes into any size liposome according to their will. The sonic waves carry energy that breaks apart the molecules of the bilayer and divides it into small pieces. These pieces are then passing through the same forces that form the naturally occurring liposomes and fold into the same shape.
Where are Liposomes Found?
You can easily find liposomes in supplement or capsule form from a laboratory. They are small artificial vesicles of spherical shape that we can create from cholesterol and natural, non-toxic phospholipids. Because of their size, hydrophobic or hydrophilic nature, liposomal vitamin C has promising systems for drug delivery.
How Do Liposomes Help with Cancer?
Aside from liposomal vitamin C, liposomes also play a crucial role in cancer treatment. Cancer is the uncontrolled growth or development of abnormal cells in the body. The cells leading to cancer are malignant. There are many ways to treat the cancer like chemotherapy, surgery, radiation treatment, etc.
With all these treatments, there are some drawbacks like living cells may get killed, loss of hair, surgery needs skilled persons, and chances of reoccurrences are also high. To avoid these issues and liposomal treatment is highly useful. Liposomal drugs have productive encapsulation capacity and show high anticancer activity with reduced toxicity preferentially cardiotoxicity.
Talk about the Major drugs formulated using liposome drug delivery such as Doxil, AmBisome, and DepoDur
Liposomes have novel drug delivery systems and defined as the vesicular structures comprising bilayers created spontaneously due to the dispersion of phospholipids in water. Liposomes help in delivering drugs by the method of diffusion rather than direct cell fusion.
The global liposome drug delivery market is driving by an increase in diagnostic and therapeutic applications. Therapeutic applications involve anticancer, anti-fungal, and anti-inflammatory drugs, with additional therapeutic gene delivery.
Major drugs formulated utilizing liposome drug delivery is Doxil, AmBisome, and DepoDur. Liposomes also play a significant role in individualized medicine. Applications involve monitoring drug delivery, determining therapy response, accurate diagnosis of diseases, and guiding minimally invasive surgeries.